Takeshi Matsuzaki Selected Research

YHO-13177

7/2011

Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo.

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Takeshi Matsuzaki Research Topics

Disease

12	Neoplasms (Cancer) 01/2021 - 10/2005
4	Carcinoma (Carcinomatosis) 01/2021 - 01/2010
4	Leukemia 07/2011 - 04/2004
3	Breast Neoplasms (Breast Cancer) 01/2014 - 07/2011
3	Stomach Neoplasms (Stomach Cancer) 01/2012 - 08/2005
3	Colonic Neoplasms (Colon Cancer) 07/2011 - 11/2002
3	Prostatic Neoplasms (Prostate Cancer) 09/2006 - 06/2003
2	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 01/2017
2	Lung Neoplasms (Lung Cancer) 07/2011 - 01/2010
2	Colorectal Neoplasms (Colorectal Cancer) 05/2011 - 10/2005
2	Rheumatoid Arthritis 12/2002 - 07/2002
1	Ovarian Neoplasms (Ovarian Cancer) 10/2012
1	Neoplasm Metastasis (Metastasis) 10/2012
1	Ascites 10/2012
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2012
1	Leukemia P388 07/2011
1	Pancreatic Neoplasms (Pancreatic Cancer) 07/2011
1	Adenocarcinoma of Lung 05/2011
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2010
1	Alzheimer Disease (Alzheimer's Disease) 08/2005
1	Fibrosarcoma 02/2004
1	Carcinogenesis 06/2003

Drug/Important Bio-Agent (IBA)

7	Irinotecan (Camptosar)FDA LinkGeneric 04/2013 - 02/2004
4	Proteins (Proteins, Gene)FDA Link 05/2017 - 08/2005
2	proto-oncogene proteins pimIBA 01/2021 - 01/2017
2	YHO-13351IBA 04/2013 - 07/2011
2	Paclitaxel (Taxol)FDA LinkGeneric 07/2011 - 01/2006
2	ProdrugsIBA 07/2011 - 05/2011
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2006 - 10/2005
2	Fluorouracil (Carac)FDA LinkGeneric 10/2005 - 08/2005
2	Messenger RNA (mRNA)IBA 12/2004 - 06/2003
2	MethyltransferasesIBA 12/2004 - 06/2003
2	hydrogen sulfite (bisulfite)IBA 12/2004 - 06/2003
2	CamptothecinIBA 04/2004 - 02/2004
1	methanesulfonic acid (methanesulfonate)IBA 01/2021
1	ThiazolidinedionesIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 05/2017
1	Antineoplastic Agents (Antineoplastics)IBA 01/2017
1	Threonine (L-Threonine)FDA Link 01/2017
1	Serine (L-Serine)FDA Link 01/2017
1	NF-kappa B (NF-kB)IBA 01/2014
1	6-(Methylsulfinyl)hexyl isothiocyanateIBA 01/2014
1	ErbB Receptors (EGF Receptor)IBA 10/2012
1	SuspensionsIBA 10/2012
1	Liposomes (Liposome)IBA 10/2012
1	YHO-13177IBA 07/2011
1	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2011
1	Mitoxantrone (Novantrone)FDA LinkGeneric 07/2011
1	Topotecan (Hycamtin)FDA LinkGeneric 07/2011
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 07/2011
1	LactonesIBA 05/2011
1	triptolideIBA 05/2011
1	Colchicine FDA LinkGeneric 05/2011
1	EnzymesIBA 05/2011
1	Cathepsin BIBA 05/2011
1	DipeptidesIBA 05/2011
1	amrubicinolIBA 01/2010
1	amrubicinIBA 01/2010
1	MethylcholanthreneIBA 01/2008
1	demethylsalvicanolIBA 11/2006
1	DiterpenesIBA 11/2006
1	AndrogensIBA 09/2006
1	Docetaxel (Taxotere)FDA Link 09/2006
1	AbietanesIBA 08/2006
1	PlatinumIBA 10/2005
1	Leucovorin (Folinic Acid)FDA Link 10/2005
1	IntegrinsIBA 08/2005
1	Cycloheximide (Cicloheximide)IBA 08/2005
1	InterferonsIBA 08/2005
1	Carrier Proteins (Binding Protein)IBA 08/2005
1	CalciumIBA 08/2005
1	Presenilin-2IBA 08/2005
1	Nerve Growth Factors (Neurotrophins)IBA 12/2004
1	DNA (Deoxyribonucleic Acid)IBA 12/2004
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 12/2004
1	Histone Deacetylase InhibitorsIBA 06/2003
1	Complementary DNA (cDNA)IBA 06/2003
1	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 06/2003
1	Sodium Salicylate (Salicylate, Sodium)IBA 12/2002
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2002
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 11/2002
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 11/2002
1	PPAR gammaIBA 07/2002
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 07/2002

Therapy/Procedure

4	Drug Therapy (Chemotherapy) 04/2013 - 09/2006
3	Therapeutics 05/2017 - 09/2006
1	Transplantation 01/2012
1	Subcutaneous Injections 01/2008